Study of laparoscopic procedure for remove of common bile duct stone and T-tube drainage / 中国普通外科杂志

Objective To study the optimal laparoscopic procedure and its indication for remove of common bile duct stone. Methods Analysis was made on the clmical data of 124 cases of laparoscopic choledocholithotomy and T tube drainage in our center.Results 82 patients underwent the improved laparoscopic procedure, alternation to open operation in 4 cases (4.9%),and the mean operating time was (80?30) min. While 42 patients were operated with traditional laparoscopic method,changing to open operation in 6 cases (14.3%),and the mean operating time was (170?40) min . The improved method could shorten the operation time and reduce the open operation rate significantly than traditional method did (P

Study on the dysfunction of the gallbladder emptying and its mechanism in diabetic patients / 中华内分泌代谢杂志

Objective To investigate the dysfunction of gallbladder emptying in diabetic patients and its possible mechanism. Methods The postprandial gallbladder emptying function and the release of pancreatic polypeptide (PP), as well as the therapeutic effect of Cisapride on gallbladder contraction were observed in 50 diabetics without cholecystolithiasis and 15 normal controls. The distributions of nitric oxide synthase (NOS) and acetylcholinesterase (AChE) in the wall of surgical removal gallbladders of 7 diabetic patients with cholecystolithiasis were also studied by histochemistry method. Results (1) The function of gallbladder emptying was distinctly lower in diabetic patients with autonomic neuropathy (AN) than that of the healthy subjects and diabetic patients without AN (NAN). (2) The postprandial release of PP in AN group was significantly lower than those in NAN group and healthy subjects. (3) The gallbladder emptying function was improved after receiving Cisapride in patients with AN. (4) Both the amount and activity of NOS and AChE in the wall of gallbladders of diabetic patients were lower than that of the non-diabetic subjects. Conclusion The dysfunction of gallbladder emptying in diabetic patients is partly due to the impaired autonomic nerve. The administration of Cisapride will improve the gallbladder emptying function of diabetic patients with AN.